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Plasmaphoresus

PLASMAPHORESUS or PLASMA EXCHANGE (PEX)

In this process the harmful auto-antibodies are removed from the blood system itself. Please read about the procedure here.

The success rate for this procedure is equally very good. Some cases of PANDAS are very extreme and may benefit from the rapid cessation of symptoms that this offers. What is not clear is if the child’s autoimmune system will recreate the negative antibodies. It has been reported that PEX has had to be repeated (as with IVIG) in a few cases. Again, prophylactic antibiotics should be maintained.

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Related studies:

Therapeutic response to plasmapheresis in four cases with obsessive-compulsive disorder and tic disorder triggered by streptococcal infections
This study follows four ADULTS receiving PEX treatment and cites, “In all 4 cases plasmapheresis treatment resulted in significant improvement in both obsessive-compulsive symptoms and tics.”