A conservative estimate is 1 in 200 children in the
U.S. alone. However, the true lifetime prevalence of PANDAS/PANS is not known.*
The statistical relevance is equal to Pediatric Cancer., Pediatric Diabetes I and II., and ALS³. The healthy outcome of a child’s life can be seriously affected, but research and treatment for PANDAS/PANS is scarce.
How do we determine the estimated lifetime prevalence of PANDAS/PANS for children 18 and under?
•Approximately 500,000 children are diagnosed with OCD in U.S.⁴
•Approximately 138,000 children are diagnosed with Tourette Syndrome in the U.S.⁵
•1.5 million+ children were diagnosed with serious anxiety/phobia/OCD/bipolar in a given year (1994-2011)⁶
•“Dr. Swedo estimates that (PANDAS) kids may make up as much as 25 percent of children diagnosed with OCD and tic disorders, such as Tourette syndrome.”⁷
*The estimated prevalence is based on PANDAS Network research.
New to understanding PANS diseases including PANDAS? Start with this guide.
PANDAS/PANS Population Analysis
Based on 700 family self-reports
AGE OF ONSET
- 1 to 3 years 11%
- 4 to 9 years 69%
- 10 to 13 years 19%
- 14+ years 1%
- OCD 37%
- TICS 14%
- BOTH 49%
- Strep 81%
- Other 19%
(Mycoplasma, Lyme, etc.)
FAMILY MEDICAL HISTORY IN FIRST OR SECOND GENERATION
Based on 100 family self-reports 70% of families reported BOTH
- Autoimmune Illness
- Strep Related Severity Illness
PANDAS/PANS POPULATION OVERVIEW
- Young age at onset: 6.5+/- 2 years for Tics and 7.4 +/- 2 years for OCD⁸
- The ratio for boy to girls is 2.6:1 ; below age 8 years, the ratio of boys to girls is 4.7:1⁸
¹KantarHealth, CancerMPact Patient metrics U.S., accessed June 28, 2012
²National Diabetes Information Clearinghouse/NDIC (information as of 2010); http://1.usa.gov/LfNKrk
³ALS Association (information as of 2011); http://bit.ly/nRR94U
⁶Centers for Disease Control and Prevention. Mental health surveillance among children – United States 2005–2011. MMWR 2013;62(Suppl; May 16, 2013):1-35.
⁷Scientific American: From Throat to Mind: Strep Today, Anxiety Later? (2010); http://bit.ly/5ro0mv
⁸Swedo et al (1998) PANDAS: Clinical Description of the First 50 Cases; http://ajp.psychiatryonline.org/data/Journals/AJP/3685/264.pdf