Research Archives

    Research Archive

2023

Association of Primary Immunodeficiencies in Parents with Psychiatric Disorders and Suicidal Behavior in Their Offspring Visit Site

2022

Worldwide Surveillance of Strep Visit Site

Understanding Parental Stress Among Parents of Children with Paediatric Acute-onset Neuropsychiatric Syndrome (PANS) in Sweden Visit Site

Immunological Causes of Obsessive-Compulsive Disorder: is it Time for the Concept of an “Autoimmune OCD” Subtype? Visit Site

Characterizing the Features, Course and Treatment of Neuropsychiatric Symptoms in Children and Adolescents with Autoimmune Encephalitis Visit Site

Group A Beta-Hemolytic Streptococcus-Induced Tic-Like Movement Disorder in an Adult: A Case Report Visit Site

2021

Treatment Barriers in PANS/PANDAS: Observations From Eleven Health Care Provider Families Visit Site

Histamine, Neuroinflammation and Neurodevelopment: A Review Visit Site

Divergent and Self-Reactive Immune Responses in the CNS of COVID-19 Patients with Neurological Symptoms Visit Site

Patient-Driven Findings of Genetic Associations for PANS and PANDAS Visit Site

Joint Hypermobility in Paediatric Acute-Onset Neuropsychiatric Syndrome – A Preliminary Case-Control Study Visit Site

Modulating Neuroinflammation in COVID-19 Patients with Obsessive-Compulsive Disorder Visit Site

Metabolomic Characterization of Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) Visit Site

PANS/PANDAS:  Clinical Experience in IVIG  for 55 children Treatment and State of the Art in Rehabilitation Approaches Visit Site
Autoimmunity and Inflammation are Associated with Childhood Tics and Obsessive-Compulsive Disorder: Transcriptomic Data Show Common Enriched Innate Immune Pathway Visit Site

SARS CoV-2 Related Paediatric Acute-Onset Neuropsychiatric Syndrome Visit Site

Long COVID isn’t as unique as we thought Visit Site

Role of Tonsillectomy and Adenoidectomy in Parental Satisfaction of Treatment for PANDA Visit Site
Evaluation of Intravenous Immunoglobulin in 21 Children Pediatric Acute-Onset Neuropsychiatric Syndrome Visit Site

Critical Flaw Found in Lab Models of the Human Blood-Brain Barrier Visit Site
Association of Rituximab Use With Adverse Events in Children, Adolescents, and Young Adults Visit Site

Patients with Abrupt Early-onset OCD due to PANS Tolerate Lower Doses of Antidepressants and Antipsychotics Visit Site

2020

Autoimmune Encephalitis: Clinical Spectrum and Management Visit Site

Nutritional and Herbal Supplements in the Treatment of Obsessive Compulsive Disorder Visit Site

How Much GAD65 Do You Have? High Levels of GAD65 Antibodies in Autoimmune Encephalitis Visit Site

The Neuroscience of Gratitude and Trauma Visit Site

Predictors and Prospective Course of PANS: A Pilot Study Using Electronic Platforms for Data Collection Visit Site
Pro-inflammatory Dopamine-2 Receptor-specific T Cells in Paediatric Movement and Psychiatric Disorders Visit Site
Autoimmune Encephalitis: When Your Body Attacks Your Brain, and People Think You’re Going Mad Visit Site
A Summary of Encephalitis Research in 2019 Visit Site
Autoantibody Biomarkers for Basal Ganglia Encephalitis in Sydenham Chorea and Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections Visit Site
Association of Primary Humoral Immunodeficiencies With Psychiatric Disorders and Suicidal Behavior and the Role of Autoimmune Diseases Visit Site
Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity Visit Site
Infectious and Autoimmune Causes of Encephalitis in Children Visit Site
Association of Pediatric Acute-Onset Neuropsychiatric Syndrome with Microstructural Differences in Brain Regions Detected Via Diffusion-Weighted Magnetic Resonance Imaging Visit Site
Are We Facing a Crashing Wave of Neuropsychiatric Sequelae of COVID-19? Neuropsychiatric Symptoms and Potential Immunologic Mechanisms Visit Site
Benefits of IVIG in Pediatric Acute-Onset Neuropsychiatric Syndrome Visit Site
Th17 Lymphocytes Drive Vascular and Neuronal Deficits in a Mouse Model of Postinfectious Autoimmune Encephalitis Visit Site
Anti-lysoganglioside and Other Anti-Neuronal Autoantibodies in Post-Treatment Lyme Disease and Erythema Migrans after Repeat Infection Visit Site
Evaluation of the Cunningham Panel in Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection (PANDAS) and Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS): Changes in Antineuronal Antibody Titers Parallel Changes in Patient Symptoms Visit Site
Clinical Approach to the Diagnosis of Autoimmune Encephalitis in the Pediatric Patient Visit Site

Hyperferritinemia and Iron Deficiency in Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome Visit Site

2019

Guidelines on the Use of Therapeutic Apheresis in Clinical Practice – Evidence-based Approach from the Writing Committee of the American Society for Apheresis: The Eighth Special Issue Visit Site

Harmful Bacteria Masquerade as Red Blood Cells to Evade the Immune System Visit Site

Focus on Cardiologic Findings in 30 Children with PANS/PANDAS: An Italian Single-Center Observational Study Visit Site

Emergence of dominant toxigenic M1T1 Streptococcus pyogenes cone during increased scarlet fever activity in England: a population-based molecular epidemilogical study Visit Site
How strep throat may spark OCD and anxiety in some kids Visit Site

Role of Tonsillectomy and Adenoidectomy in Parental Satisfaction of Treatment for PANDA Visit Site

Mannose-Binding Lectin 2 Gene Polymorphism in PANDAS Patients Visit Site

A Pediatric Infectious Disease Perspective on Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection and Pediatric Acute-onset Neuropsychiatric Syndrome Visit Site
What Parents Should Know About Infections and Mental Health Visit Site

PANDAS: What Occupational Therapy Practitioners Should Know Visit Site

Immune-Related Comorbidities in Childhood-Onset Obsessive Compulsive Disorder: Lifetime Prevalence in the Obsessive Compulsive Disorder Collaborative Genetics Association Study Visit Site

Establishing a Pediatric Acute-Onset Neuropsychiatric Syndrome Clinic: Baseline Clinical Features of the Pediatric Acute-Onset Neuropsychiatric Syndrome Cohort at Karolinska Institutet Visit Site

Clinical-Serological Characterization and Treatment Outcome of a Large Cohort of Italian Children with Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection and Pediatric Acute Neuropsychiatric Syndrome Visit Site

PANDAS and PANS: Clinical, Neuropsychological, and Biological Characterization of a Monocentric Series of Patients and Proposal for a Diagnostic Protocol Visit Site

Infections and Drugs to Treat Them Tied to Eating Disorders in Teens Visit Site

PANDAS/PANS in Childhood: Controversies and Evidence Visit Site

The impact of attention deficit hyperactivity disorder in obsessive-compulsive disorder subjects [955 adults with OCD, 13.7% incidence of traits as pediatric onset with rheumatic fever] Visit Site

Autoimmune Diseases and Psychotic Disorders. (view video of Dr. Michael Benros speaking at 2018 Columbia Conference here) Visit Site

Immunoglobulin A Dysgammaglobulinemia is Associated with Pediatric-Onset Obsessive-Compulsive Disorder Visit Site

Differential binding of antibodies in PANDAS patients to cholinergic interneurons in the striatum Visit Site

PANDAS and PANS: Clinical, Neuropsychological, and Biological Characterization of a Monocentric Series of Patients and Proposal for a Diagnostic Protocol Visit Site

Neuropsychiatric Consequences of Childhood Group A Streptococcal Infection: A Systematic Review of Preclinical Models Visit Site

Admission diagnoses of patients later diagnosed with autoimmune encephalitis Visit Site

2018

Final Report Summary – EMTICS (European Multicentre Tics in Children Studies) Visit

The Burden of Caring for a Child or Adolescent With Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS): An Observational Longitudinal Study Visit Site

Treatment of PANDAS and PANS: a systematic review Visit Site

Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection (PANDAS): Clinical Manifestations, IVIG Treatment Outcomes, Results from a Cohort of Italian Patients Visit Site

An Atypical Presentation of Pediatric Acute Neuropsychiatric Syndrome Responding to Plasmapheresis Treatment Visit Site

European Advocacy Organizations Response to PANDAS/PANS Article Visit Site

Family Impacts Reported By Parents Raising Children With Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) Visit Site

(Mayo Clinic Report on Worldwide AE Prevalence) When the Body Attacks the Brain: Immune System Often to Blame for Encephalitis, Study Finds Visit Site

2017

Survey of 600+ PANDAS/PANS Families: Treatment of Pediatric Acute-Onset Neuropsychiatric Disorder in a Large Survey Population Visit Site

Survey of 600+ PANDAS/PANS Families: A Survey of Pediatric Acute-Onset Neuropsychiatric Syndrome Characteristics and Course Visit Site

Overview of Treatment of Pediatric Acute-Onset Neuropsychiatric Syndrome Visit Site

Clinical Management of PANS: Part I–Psychiatric and Behavioral Interventions Visit Site

Clinical Management of PANS: Part II—Use of Immunomodulatory Therapies Visit Site

Clinical Management of PANS: Part III—Treatment and Prevention of Infections Visit Site

Pediatric Acute-Onset Neuropsychiatric Syndrome Response to Oral Corticosteroid Bursts: An Observational Study of Patients in an Academic Community-Based PANS Clinic Visit Site

Course of Neuropsychiatric Symptoms After Introduction and Removal of Nonsteroidal Anti-Inflammatory Drugs: A Pediatric Observational Study Visit Site

Effect of Early and Prophylactic Nonsteroidal Anti-Inflammatory Drugs on Flare Duration in Pediatric Acute-Onset Neuropsychiatric Syndrome: An Observational Study of Patients Followed by an Academic Community-Based Pediatric Acute-Onset Neuropsychiatric Syndrome Clinic Visit Site

A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive-Compulsive Disorder. Visit Site

Association of Streptococcal Throat Infection With Mental Disorders: Testing Key Aspects of the PANDAS Hypothesis in a Nationwide Study Visit Site

Cognitive Behavioral Therapy And Acceptance And Commitment Therapy As Augmentation Treatment For (Pandas): A Case Report Visit Site

Hello from the Other Side: How Autoantibodies Circumvent the Blood–Brain Barrier in Autoimmune Encephalitis Visit Site

Palatal Petechiae in the Absence of Group A Streptococcus in Pediatric Patients with Acute-Onset Neuropsychiatric Deterioration: A Cohort Study Visit Site

Impact of PANS and PANDAS Exacerbations on Occupational Performance: A Mixed-Methods Study Visit Site

Prospective Longitudinal Analysis of Immune Responses in Pediatric Subjects After Pharyngeal Acquisition of Group A Streptococci Visit Site

Improvement Of Psychiatric Symptoms In Youth Following Resolution Of Sinusitis Visit Site

Hidden Invaders: Infections Can Trigger Immune Attacks On Kids’ Brains, Provoking Devastating Psychiatric Disorders Visit Site

2016

Vitamin D Deficiency in Obsessive-Compulsive Disorder Patients with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections: A Case Control Study Visit Site

The Neuropsychological Profile Of Children With Basal Ganglia Encephalitis: A Case Series Visit Site

Randomized, Controlled Trial of Intravenous Immunoglobulin for Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections Visit Site

Rapid Eye Movement Sleep Abnormalities in Children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS). Visit Site

Pediatric Autoimmune Disorders Associated with Streptococcal Infections and Tourette’s Syndrome in Preclinical Studies Visit Site

Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) Visit Site

2015

Implications for Advanced Practice Nurses When Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) Is Suspected: A Qualitative Study Visit Site

LTherapeutic Plasma Apheresis as a Treatment for 35 Severely Ill Children and Adolescents with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections Visit Site

Use of Intravenous Immunoglobulin in the Treatment of Twelve Youths with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections Visit Site

Antineuronal Antibodies in a Heterogeneous Group of Youth and Young Adults with Tics and Obsessive-Compulsive Disorder Visit Site

Clinical Presentation of Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections in Research and Community Settings Visit Site

Five Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome of Differing Etiologies Visit Site

Multidisciplinary Clinic Dedicated to Treating Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome: Presenting Characteristics of the First 47 Consecutive Patients Visit Site

Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells Visit Site

Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells Visit Site

Detection Of Anti-streptococcal, Antienolase, And Anti-neural Antibodies In Subjects With Early-onset Psychiatric Disorders Visit Site

Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus Immunology: A Pilot Study Visit Site

Characterization of B-Cells in tonsils of patients diagnosed with pediatric autoimmune neuropsychiatric disorder associated streptococcus Visit Site

The Role of Tonsillectomy in the Treatment of Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS) Visit Site

Sydenham Chorea and PANDAS in South Africa: Review of Evidence and Recommendations for Management in Resource-Poor Countries Visit Site

2014

Clinical Evaluation of Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS): Recommendations from the 2013 PANS Consensus Conference Visit Site

Disordered Eating and Food Restrictions in Children with PANDAS/PANS Visit Site

Cefdinir for Recent-Onset Pediatric Neuropsychiatric Disorders: A Pilot Randomized Trial Visit Site

Characterization of the Pediatric Acute-Onset Neuropsychiatric Syndrome Phenotype Visit Site

PANDAS and Comorbid Kleine–Levin Syndrome Visit Site

Pediatric Inflammatory Brain Diseases: A Diagnostic Approach Visit Site

Post-infectious Autoimmune Disorders: Sydenham’s Chorea, PANDAS and Beyond Visit Site

Evaluation of Basal Ganglia and Thalamic Inflammation in Children With Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infection and Tourette Syndrome-A Positron Emission Tomographic (PET) Study Using 11C-[R]-PK11195 Visit Site

Behavioral and neural effects of intra-striatal infusion of anti-streptococcal antibodies in rats Visit Site

The Curious Case Of The “Inseparable Child” Visit Site

A Link Between Perianal Strep and Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection (PANDAS) Visit Site

2013

Periodic Fever and Hyperimmunoglobulin D Syndrome in a Boy with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Group A β-Hemolytic Streptococcus Visit Site

From Research Subgroup to Clinical Syndrome: Modifying the PANDAS Criteria to Describe PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) Visit Site

Dopamine Receptor Autoantibodies Correlate with Symptoms in Sydenham’s Chorea Visit Site

Clinical Factors Associated with PANDAS Visit Site

Autoimmune Encephalitis – History & Current Knowledge Visit Site

2010–2012

Passive Transfer Of Streptococcus-induced Antibodies Reproduces Behavioral Disturbances In A Mouse Model Of Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infection. Visit Site

The Relationship Between Group A Beta Hemolytic Streptococcal Infection And Psychiatric Symptoms: A Pilot Study Visit Site

Executive and Attention Functioning Among Children in the PANDAS Subgroup Visit Site

Mycoplasma pneumoniae infection and obsessive-compulsive disease: a case report Visit Site

Challenges in the Identification and Treatment of PANDAS: A Case Series Visit Site

Therapeutic Response to Plasmapheresis in Four Cases with Obsessive-Compulsive Disorder and Tic Disorder Triggered by Streptococcal Infections Visit Site

Certain Eating Disorders May Be a Neuropsychiatric Manifestation of PANDAS: Case Report Visit Site

Relationship Of Movements And Behaviors To Group A Streptococcus Infections In Elementary School Children Visit Site

Group A Streptococcus and its Antibiotic Resistance Visit Site

Antibody-mediated Neuronal Cell Signaling In Behavior And Movement Disorders Visit Site

Strep and Urinary Frequency: Is There a Connection? Visit Site

Viable Group A Streptococci in Macrophages during Acute Soft Tissue Infection Visit Site

Antibiotic Prophylaxis With Azithromycin Or Penicillin For Childhood-onset Neuropsychiatric Disorders Visit Site

Encephalitis Lethargica Syndrome: 20 New Cases And Evidence Of Basal Ganglia Autoimmunity Visit Site

Pandas: Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections–an Uncommon, But Important Indication For Tonsillectomy. Visit Site

Immune Response to Group A Streptococcal C5a Peptidase in Children: Implications for Vaccine Development Visit Site

Tourette’s Syndrome: A Cross Sectional Study To Examine The PANDAS Hypothesis Visit Site

Post-streptococcal autoimmune disorders of the central nervous system Visit Site

Mimicry and Autoantibody-mediated Neuronal Cell Signaling in Sydenham Chorea Visit Site

Pediatric Autoimmune Neuropsychiatric Disorders and Streptococcal Infections: Role Of Otolaryngologist Visit Site

The Pandas Subgroup: Recognition And Treatment Visit Site

PANDAS Variant and Body Dysmorphic Disorder Visit Site

Therapeutic Plasma Exchange And Intravenous Immunoglobulin For Obsessive-compulsive Disorder And Tic Disorders In Childhood Visit Site

Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections: Clinical Description of the First 50 Cases Visit Site

Lyme Disease and Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (Pandas): An Overview Visit Site

Behavioral, Pharmacological, And Immunological Abnormalities After Streptococcal Exposure: A Novel Rat Model Of Sydenham Chorea And Related Neuropsychiatric Disorders Visit Site

Neurocognitive Functioning in Youth With Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcus Visit Site

Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcus In Identical Siblings. Visit Site

Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS): An Indication For Tonsillectomy Visit Site

The Immunobiology of Tourette’s Disorder, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus, and Related Disorders: A Way Forward Visit Site

Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS): A Case Report Visit Site

Role of IL-1 Beta in the Development of Human TH17 Cells: Lesson from NLPR3 Mutated Patients Visit Site

The Interleukin 1 beta (IL1B) Gene is Associated with Failure to Achieve Remission and Impaired Emotion Processing in Major Depression Visit Site